にしても

にしても is used to introduce a premise that might be extreme or contrary to the speaker’s expectation, and then contrasts it with the subsequent result, decision, or evaluation. It emphasizes that regardless of the situation described in the premise, the main statement still holds or another conclusion follows. It often translates as “even if …,” “even though …,” or “even when …,” and can carry a slightly formal or emphatic nuance. It is common in both spoken and written Japanese, especially in making concessions or presenting possible scenarios. Typical contexts include: talking about plans that will proceed despite conditions, or evaluating possibilities where the premise is uncertain or challenging. Note that the preceding clause is not necessarily a complete condition; it sets up a hypothetical or representative situation for contrast.